Mezo Taps Aerodrome for Bitcoin DeFi Liquidity on Base

Mezo, a decentralized lending platform for Bitcoin, announced a strategic partnership with Aerodrome Finance on Thursday. The collaboration establishes Aerodrome as the primary liquidity hub for Mezo’s native tokens on the Base network.

Under the agreement, Mezo will distribute 2.25% of its total token supply to Aerodrome’s veAERO voters over a 30-day period.

The move aims to incentivize deep liquidity for the MEZO token and MUSD, a Bitcoin-backed Mezo’s stablecoin.

The partnership targets Aerodrome’s sophisticated user base, which utilizes a vote-escrow model to direct protocol emissions. In this system, users lock tokens to gain voting power and rewards, helping guide liquidity and incentives in a way that supports long-term stability.

Its veAERO voters include some of the largest and most experienced DeFi participants, including protocols and high-net-worth traders who helped establish sustainable yield models on Base.

Mezo has adapted the vote-escrow model for Bitcoin lending through its Mezo Earn platform, described internally as “Aerodrome for Bitcoin lending.” The partnership targets these experienced voters, creating a bridge from Base’s vote-escrow economy to Bitcoin DeFi.

The setup is designed to encourage veAERO holders to direct liquidity toward Mezo trading pairs, supporting deeper liquidity for MEZO and enabling MUSD to serve as collateral within Bitcoin’s DeFi ecosystem.

The announcement follows Mezo’s "Bring Bitcoin Home" campaign, an initiative that successfully migrated approximately $23 million in Bitcoin-linked assets, including tBTC, cbBTC, and WBTC, from Ethereum to the Mezo mainnet. 

Current network data reflects this growth, with Total Value Locked reaching $76.3 million and lifetime MUSD volume hitting approximately $500 million.

The platform currently serves more than 43,500 mainnet users and has issued over 2,000 loans at a fixed 1% APR. Yield for Bitcoin lockers currently averages 4% APR, a figure derived from real protocol activity including borrower interest, origination fees, and swap fees from Mezo’s internal decentralized exchange.

Mezo is backed by $28.5 million in seed funding, a round led by Pantera Capital with participation from Paradigm, a16z, and Polychain. To support institutional adoption, the protocol integrates with Anchorage Digital for compliant custody.

The protocol’s security framework includes audits by Quantstamp and Thesis Defense, while its validator set is operated by industry veterans including P2P and Chorus One. 

Mezo is a product of Thesis*, a venture studio that has developed Bitcoin-adjacent technologies since 2014, including Fold and tBTC.

This deal brings skilled DeFi users from Base into Bitcoin, helping MEZO and MUSD get more liquidity. It marks a step toward making Bitcoin lending and stablecoins more usable and better connected to the wider DeFi world.

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