Semler Scientific treats Bitcoin as a long-term asset, sets sights on 105,000 BTC by 2027

Semler Scientific, a publicly listed US healthcare technology company, is doubling down on its Bitcoin strategy in a big way.

The firm said on Thursday that it planned to amass 105,000 Bitcoins by the end of 2027, enough to make it one of the world’s largest corporate holders of digital assets.

The company’s Bitcoin purchasing plan is set to be rolled out over three years, led by Joe Burnett, the director of Bitcoin strategy. Semler is hoping to own 10,000 BTC by the end of 2025. That figure will increase to 42,000 BTC by the end of 2026 and to 105,000 BTC by the end of 2027.

That approach is part of a broader trend among publicly held companies that are forward-looking and increasingly considering Bitcoin not as a speculative bet but as a long-term store of value and a core treasury asset.

Semler treats Bitcoin as a long-term asset

Semler’s dive into Bitcoin is no flight of fancy. The company’s been on this path since May 2024, when it jumped onto what it calls the “Bitcoin Standard.” Since then, Semler has pivoted to a Bitcoin bull and is among the most vocal corporate cheerleaders for cryptocurrency.

On June 4, 2025, the company held 4,449 BTC valued at $462 million. That would make it one of the 15 biggest Bitcoin collectives in the world.

However, the outfit’s 287% BTC yield and $177 million in profit from its Bitcoin holdings as of early June are more remarkable. These returns reinforce the firm’s argument that Bitcoin is not just a hedge but also a potent value-generating asset.

Burnett, who has spoken with some of the smartest economists, investors, and Bitcoin thinkers across every format, will help Semler build its thesis around education, macro insights, and treasury diversification with Bitcoin.

It also indicates a more deliberate, permanent establishment of Bitcoin strategy within the company’s executive ranks.

Semler builds reputation as Bitcoin strategy leader

Semler Scientific’s approach puts it in the company of firms such as Strategy, currently the world’s largest corporate holder of Bitcoin. With Semler’s 15,000 BTC to date, compared to Strategy’s 214,400 BTC, closing this gap in the longer term is truly underway.

It is now the second US public company to adopt the Bitcoin Standard, following Strategy. According to The Block data, almost 230 companies worldwide have adopted similar Bitcoin treasury strategies.

Semler’s move is part of a growing institutional trend toward Bitcoin, such as the growing number of US spot Bitcoin ETFs on the heels of more positive regulatory clarity and greater macroeconomic uncertainty, leading many to diversify their asset portfolio.

The company now trades on the Nasdaq under the trading symbol SMLR. It now trades at about $32 a share for a market capitalization of about $375 million. Semler’s aggressive crypto play has garnered interest from traditional investors and Bitcoin enthusiasts. Though it has been relatively modest in size, the fund has seen users plow money into it at a rapid clip.

In an industry where few healthcare companies have been brave enough to take such a step, Semler establishes a distinct brand that blends healthcare innovation with Bitcoin maximalism. Assuming its plan proceeds according to schedule, the company may soon become one of the biggest non-financial corporate owners of Bitcoin in the next two years.

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