Health prediction markets

Health prediction markets price pandemics, case counts and drug approvals. 25 health questions are trading on Polymarket and Kalshi, led by “New pandemic in 2026”. This is one of the smallest categories, so prices can rest on little money. Check each market's volume before you read much into its price.

Updated

19
open on Polymarket
6
open on Kalshi
15
priced on both
0
closing this week

Most traded health markets

Health markets priced on both venues

The busiest health markets both venues list. When the prices differ, the cheaper side costs you less for the same payout.

Every health market, priced

MarketChance24h volumeVenues
Polymarket · Kalshi · resolves Dec 31, 2026
6%$14K2 · compareTrade
Polymarket · resolves Oct 31, 2026 · Busiest: October 15, 2026
9%$10K1Trade
Polymarket · Kalshi · resolves Dec 31, 2026 · Busiest: Canada
13%$4K2Trade
Polymarket · resolves Dec 31, 2026
5%$3K1Trade
Polymarket · resolves Dec 31, 2026
2%$9591Trade
Polymarket · resolves Dec 31, 2026 · Busiest: ↑7.5k
15%$7501Trade
Kalshi · resolves Jan 1, 2029 · Busiest: At least 2000
97%$5011Trade
Polymarket · resolves Oct 31, 2026 · Busiest: 4300+
92%$3161Trade
Polymarket · Kalshi · resolves Dec 31, 2026 · Busiest: November 30
12%$2492Trade

Chance is the favourite's price on a board of outcomes, the favoured side of a match, or the named market's Yes price, on its venue.

Polymarket or Kalshi for health markets?

Polymarket lists 19 open health events right now, and Kalshi lists 6.

Neither venue trades much here yet, so compare both prices before you buy.

Polymarket
Regulated
CFTC-designated, via Polymarket US
You fund with
Debit card, ACH, wire in the US; crypto, held as pUSD (Polygon) abroad
Open health markets
19 markets
Fees
Polymarket's fees
Kalshi
Regulated
CFTC-designated exchange
You fund with
ACH, RTP, debit card and 7 more
Open health markets
6 markets
Fees
Kalshi's fees

$50 bonusNew to Kalshi? Trade $20, get a $50 bonus through our link. US only, 18+. Offer terms

Check your state before you sign up · Kalshi vs Polymarket in full · Every app compared

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What health markets you can trade

Most health markets ask whether something happens by a date, or how high a case count climbs.

  • Whether a pandemic is declared this year
  • Case counts for diseases such as measles
  • FDA approvals and filings
  • Public health emergencies

What moves health odds

Official data moves these markets, such as weekly case reports or an agency's decision.

Volume is low, so one order can move a price a long way. That is the honest limit of this category.

More health markets

Other categories

Common questions

What are health prediction markets?

Markets on health outcomes, such as a pandemic declaration or a case count. Each price reads as a probability.

Why are health markets so quiet?

Few traders follow them. With little money on a market, its price is a weaker signal.

How do health markets settle?

On the official source the rules name, such as a public health agency's published count.

Can I trade health markets in my state?

In most states, yes, on Polymarket US or Kalshi. Check your state for any action against specific contracts.